Melanoma Metastatic to the Mandible: Symptoms Precede Imaging Findings

Imaging of metastatic melanoma

Cutaneous cancer is now the most common human malignancy and in the UK malignant melanoma comprises 11% of all skin cancers. Eighty percent of malignant melanoma is thought to be related to excessive exposure to sunlight, particularly in childhood. Although the least common skin cancer, malignant melanoma is the most deadly. In 1999 it killed over 1600 individuals in the UK and by 2004, in the ...

Fulminant hepatic failure due to metastatic choroidal melanoma

Nasopharyngeal Carcinoma Metastatic to the Mandible

Nasopharyngeal carcinoma (NPC) is one of the most common malignancies in the head and neck region, especially among those of Chinese origin. NPC has multifactorial aetiologies including genetic susceptibility, consumption of food with high salt content, and the Epstein-Barr virus. The primary tumour usually arises from the lateral walls of the nasopharynx and is characterized by a rich sub-muco...

Imaging findings of Ewing's sarcoma in the mandible.

First described by James Ewing in 1921, Ewing's sarcoma (ES) or Ewing's tumor is one of the most aggressive bone tumors known. ES is an uncommon intra-osseous malignant tumor of questionable pathogenesis that occurs in children and young adults. Reports indicate that only 2 to 7% of cases involve the maxillofacial region, usually the mandible ramus, and few reported cases have involved the maxi...

Lobular adenocarcinoma of the breast metastatic to the mandible.

Ipratropium bromide (Atrovent) is a commonly and widely used antimuscarinic bronchodilator with very few side-effects. Although buccal ulceration and haemorrhagic bullae affecting the palate have been reported with ipratropium bromide (IB) they do not appear in the British National Formulary and are not mentioned in the manufacturer’s (Atrovent) product information either. Therefore, we believe...